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31st EASDec Annual Meeting, 28th – 30th October 2021, Odense, Denmark.

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12:30 Registration and lunch
13:45 How to navigate physically and virtually at the EASDec 2021 hybrid meeting
  Chair of Local Organizing Committee, Professor Jakob Grauslund, Odense
14:00 The Moonshot initiative
  Professor Tom Gardner, Ann Arbor
14:15 Satellite Symposium: Diabetes and diabetic macular oedema – where are we today?
  Moderator: Professor Jakob Grauslund, Odense
  Welcome and introduction
  Professor Jakob Grauslund, Odense
  Diabetes from the endocrinologist’s perspective: what is important for the ophthalmologist to know?
  Professor Mikael Rydén, Stockholm
  Diabetes from the ophthalmologist´s perspective: what is important for the endocrinologist to know?
  Professor Jakob Grauslund, Odense
15:15 Highlights and future directions from the 5th conference of Screening for Diabetic Retinopathy in Europe (www.drscreening2005.org.uk)

Moderators: Professor Tunde Peto, Belfast, and Dr Caroline Styles, Dunfermline
16:00 Break
16:30 Satellite Symposium: Inflammation and the diabetic eye
  Alimera Sciences
  Chair: Professor Simon Harding, Liverpool
  Welcome & Introduction
  Professor Simon Harding, Liverpool
  Neuroinflammation: A key player in diabetic retinopathy/diabetic macular edema
  Professor Rafael Simó, Barcelona
  Imaging biomarkers to define DME chronicity and support therapeutic decision-making in DME
  Professor Stela Vujosevic, Milan
  Assessing the long-term safety and visual outcomes following corticosteroid therapy in patients with DME
  Professor Tunde Peto, Belfast
17:30 Satellite Symposium: Expanding Diabetic Eye Disease Detection and Management with Ultra-widefield Imaging
  Chair: Professor Tunde Peto, Belfast
  The Essential Role of Ultra-widefield in all Diabetic Eye Clinics
  Dr Stela Vujosevic, Milan
  Ultra-widefield Fluorescein Angiography: What Lies Unseen?
  Dr Paolo Silva, Boston
  The Role of the Peripheral Retina in Diabetic Retinopathy: From Basic Science to Town Planning
  Ms Laura Cushley (PhD Researcher), Belfast
  Virtual Diabetic Retinopathy Clinics, Artificial Intelligence and UWF-Guided Swept Source OCT
  Professor Tunde Peto, Belfast
18:30 Official opening of EASDec
  President of EASDec, Professor Rafael Simó, Barcelona
  Chair of Organizing Committee, Professor Jakob Grauslund, Odense 
18:45 Annual Meeting Welcome Reception (see Social Events for further information)
  HC Andersen's House
  Hans Jensen Stræde 45 (100 meters from conference venue)
  Dress code: Casual
  Social event registration needed for participation
  A culinary fairy tale experience:
  18:45 Welcome and drink
  18:50 Exhibition and appetizers
  19:30 Buffet (drinks included)
21:00 End of the day



08:00 Registration
09:00 Introduction and welcome
  President of EASDec, Professor Rafael Simó, Barcelona
  Chair, Local Organizing Committee, Professor Jakob Grauslund, Odense
09:15 Session 1: Experimental and translational research in diabetic eye complications
  Chairs: Professor Reinier Schlingemann, Amsterdam, and Associate Professor Patrice Fort, Ann Arbor
09:16 Topical ocular administration of sitagliptin, a DPP-4 inhibitor, prevents the downregulation of neuroretinal presynaptic proteins induced by diabetes (abstract 30)
  Dr Cristina Hernandez, Barcelona
09:27 Characterization of a new immortalized human microglial cell line and its pro-inflammatory activation (abstract 35)
  Dr Aurora Mazzeo, Torino
09:38 Towards a better understanding of PLVAP in vascular permeability: a proteomic approach to identify interacting partners of PLVAP (abstract 95)
  Ms Esmeralda Bosma, Amsterdam
09:49 Mapping the daily rhythmic transcriptome in the diabetic retina (abstract 68)
  Dr Eleni Beli, Belfast
10:00 mmunomodulation of microglia/macrophage interaction and its effect in diabetic retinopathy progression (abstract 55)
  Ms Fatima Cano-Cano, Cadíz
10:11 Winner of the EASDec Young Investigator Award in honour of Anne-Katrin Sjolie
  Circadian clocks in diabetic retinal endothelial cells (abstract 70)
  Ms Hanagh Winter, Belfast
10:22 Session conclusions by the moderators
10:25 Coffee break
10:40 Session 2: Epidemiology of ocular and systemic complications in diabetes
  Chair: Professor Morten Moe, Oslo, and Professor Simon Harding, Liverpool
10:41 Free-registration award-winning abstract for young scientist
  Five-year incidence and progression of age-related macular degeneration in people with diabetes (abstract 80)
  Ms Dewi Romdhoniyyah, Liverpool
10:52 Relationship between diabetic retinopathy and systemic neurodegenerative diseases: a systematic review and meta-analysis (abstract 16)
  Professor Jakob Grauslund, Odense
11:03 Non-attendance at diabetic eye screening in the Danish nationwide screening program (abstract 50)
  Dr Anne Thykjær, Odense
11:14 Association between diabetic retinopathy and glaucoma: results from a national screening program (abstract 41)
  Dr Signe Sperling, Odense
11:25 Prevalence and progression of diabetic retinopathy and macular edema during pregnancy in women with type 1 and type 2 diabetes (abstract 51)
  Professor Elisabeth Mathiesen, Copenhagen
11:36 Do systematic diabetic retinopathy screening programmes prevent severe sight impairment? (abstract 91)
  Dr Caroline Styles, Dunfermline
11:47 Session conclusions by the moderators
11:50 Eva Kohner Lecture: Detecting diabetic retinopathy – timing is everything
  Chair: Professor Tunde Peto, Belfast
  Awardee: Professor Simon Harding, Liverpool
12:35 Lunch
  12:35-13:00: Poster presenters
13:00-13:30: All
13:00 Session 3: Poster session


1 - Experimental research
Moderator: Dr Cristina Hernandéz, Barcelona


Free-registration award-winning abstract for young scientist
1-01: Optimization of immunofluorescent detection of vascular markers on frozen human retinal sections (abstract 45)
Ms Noëlle Bakker, Amsterdam

1-02: Correlation between the aqueous humor proteome and severity of diabetic macular edema (abstract 28)
Dr Lasse Cehofski, Odense


2 – Diabetic eye screening
Moderator: Dr Dag Fosmark, Oslo


Free-registration award-winning abstract for young scientist
2-01: Identifying undetected prevalent disease: the first-pass effect in diabetic retinopathy screening programs (abstract 47)
Dr Recivall Salongcay, Manila

Free-registration award-winning abstract for young scientist
2-02: Five year outcomes of diabetic eye screening in patients aged 80 years (abstract 40)
Ms Nichola Albutt, Birmingham

2-03: A qualitative study on barriers and enablers to uptake of diabetic retinopathy screening by people with diabetes in the western province of Sri Lanka (abstract 83)
Dr Mapa Piyasena, London

2-04: Inclusion of diabetic retinopathy screening strategies in national level diabetes care planning in low and middle-income countries: a scoping review (abstract 67)
Dr Katie Curran, Belfast

2-05: Out of hours diabetic eye screening – a high risk group (abstract 72)
Mr Richard Aldred, Gloucestershire

2-06: Diabetic retinopathy in pregnancy: screening attendance rates and development of disease (abstract 25)
Ms Leanne Bird, Birmingham

Free-registration award-winning abstract for young scientist
2-07: Progression of diabetic retinopathy in type 1 and 2 diabetes during pregnancy and postpartum in the Danish national diabetes retinopathy screening program (abstract 89)
Ms Janni Larsson, Roskilde

2-08: Treatment and follow up of patients graded as R3 (proliferative retinopathy) by diabetic retinopathy screening programme (DRSP) in Belfast, Northern Ireland (abstract 59)
Dr Adele Heaney, Belfast

2-09: Diabetic retinopathy screening in individuals with severe mental illness (abstract 20)
Mr John Sandford, Birmingham

2-10: Diabetic eye screening outcomes after non-attendance for three or more years (abstract 27)
Ms Latesha Brown, Birmingham

2-11: Diabetes-related blindness between 1999 and 2018 in Denmark (abstract 92)
Dr Søren Blindbæk, Odense

2-12: A retrospective analysis of factors affecting attendance at the Northern Ireland Diabetic Eye Screening Programme in young people with diabetes aged 12-26 (abstract 38)
Ms Laura Cushley, Belfast

2-13: Impacts on eye health for patients who fail to attend hospital ophthalmology appointments (abstract 88)
Ms Joanne Harmon, Cork

2-14: Updating a diabetic eye screening programme - a long and winding road (abstract 79)
Ms Irene Stratton, Gloucester


3 - Epidemiology
Moderator: Dr Karl-Johan Hellgren, Karlstad


3-01: Diabetic retinopathy and risk of prevalent and 5-year incident cardiovascular disorders in type 2 diabetes (abstract 37)
Ms Lonny Stokholm, Odense

3-02: Characteristic features of diabetic retinopathy (DR) in UK BIOBANK (UKBB) (abstract 75)
Dr Michaell Quinn, Belfast

3-03: Characteristics of diabetic retinopathy in the Funen Diabetes Database based on latent class analysis (abstract 61)
Dr Morten Larsen, Odense

3-04: Progression to proliferative diabetic retinopathy in the Danish Registry of Diabetic Retinopathy (abstract 64)
Dr Sebastian Dinesen, Odense

3-05: Relationship between diabetic retinopathy and primary open-angle glaucoma
in patients with diabetes mellitus (abstract 44)
Ms Marianne Kjærsgaard, Odense

3-06: Inverse cross-sectional and longitudinal relations between diabetic retinopathy and obstructive sleep apnea in type 2 diabetes: results from a national screening program (abstract 13)
Professor Jakob Grauslund, Odense

Free-registration award-winning abstract for young scientist
3-07: Incidence of acute angle closure glaucoma in the Northern Ireland Diabetic Eye Screening Programme (DESPNI) between 2016-2021 (abstract 102)
Dr Matt O’Donell, Belfast

3-08: Diabetic retinopathy as a potential marker of protection of prevalent and incident migraine: results from a national cohort study (abstract 14)
Dr Anna Vergmann, Odense

3-09: Diabetic retinopathy and chronic respiratory failure: a national register-based cohort study (abstract 34)
Dr Benjamin Thinggaard, Odense

3-10: Diabetic retinopathy as a potential marker of Parkinson’s disease: results from a nationwide register-based cohort study (abstract 19)
Ms Maria Larsen, Odense

3-11: Diabetic retinopathy and risk of major depression: bidirectional results from a Danish register-based nationwide cohort study (abstract 33)
Dr Frederik Pedersen, Odense


4 - Clinical studies
Moderator: Professor Toke Bek, Aarhus


4-01: Disorganisation of Retinal Inner Layers (DRIL) in participants with diabetic macular oedema: The RELIGHT Study (abstract 96)
Ms Catherine Jamison, Belfast

4-02: Risk of progression of type 2 diabetes individuals with non-proliferative retinopathy: Characterization of phenotypes in a 1-year follow-up study (abstract 36)
Dr Luisa Ribeiro, Coimbra

4-03: Comparison of mean HbA1c value and ΣexcessA1C index as predictors of retinopathy development at different diabetes duration (abstract 63)
Dr Akira Hirose, Tokyo

4-05: Subjective visual disturbances in relation to fluctuating blood glucose levels in adult patients with diabetes mellitus: results from a pilot study (abstract 43)
Mr Martin Rasmussen, Odense

4-06: Is visual function altered in people with uncomplicated type 2 diabetes or with early diabetic retinopathy? (abstract 71)
Dr Karl-Johan Hellgren, Karlstad

4-08: Dry eye symptoms and signs in patients with type 2 diabetes (abstract 97)
Ms Siv Sandvik, Kongsberg

4-09: The statistician will see you now – how to make the best of a scarce resource (abstract 77)
Ms Irene Straton, Gloucester


5 - Retinal imaging
Moderator: Dr Javad Hajari, Copenhagen


5-01: The retinal oxygen saturation can be used to differentiate retinal neovascularisations from intraretinal microvascular abnormalities (IRMAs) in diabetic retinopathy (abstract 90)
Dr Line Petersen, Aarhus

5-02: The importance of optical coherence tomography (OCT) for identification of clinically significant macular oedema (CSMO) in UK BIOBANK (UKBB) (abstract 78)
Dr Barbra Hamill, Belfast

5-03: Comparison of different metrics for the identification of capillary closure in diabetic retinopathy using OCTA (abstract 57)
Dr Inês Marques, Coimbra

5-04: Suspected diabetic retinopathy (DR) related changes in UK BIOBANK (UKBB) (abstract 103)
Mr Alan Sproule, Belfast

5-05: Retinal vessel density, vessel diameter and oxygen saturation are associated with non-proliferative diabetic retinopathy in young patients with type 1 diabetes (abstract 65)
Dr Nina Veiby, Oslo

5-06: Localization of retinal lesions in diabetic retinopathy in a virtual ocular learning platform (VIOLA) (abstract 73)
Dr Malin Lundberg Rasmussen, Odense

5-07: Agreement between experts in the detection of diabetic retinopathy associated lesions in a virtual ocular learning platform (VIOLA) (abstract 18)
Mr Martin Hubel, Odense

Free-registration award-winning abstract for young scientist
5-08: Optical coherence tomography (OCT) for diabetic maculopathy in a digital surveillance clinic (abstract 39)
Ms Adele Farnsworth, Birmingham


6 - Automated screening
Moderator: Associate Professor Malin Lundberg Rasmussen, Odense


6-01: Detection of diabetic retinopathy lesions using deep learning based semantic segmentation in retinal 45 degrees 6-field images (abstract 76)
Mr Jakob Andersen, Odense

Free-registration award-winning abstract for young scientist
6-02: Testing the performance of risk prediction models to determine progression to referable diabetic retinopathy (RDR) in an Irish type 2 diabetes cohort (abstract 58)
Dr John Smith, Belfast

6-03: Comparing SIVA and VAMPIRE for vascular geometric findings in patients with type 1 diabetes (abstract 26)
Dr Sami Dabbah

6-04: CHIldren Living with Diabetes See and Thrive with AI Review: CHILDSTAR (abstract 86)
Ms Noelle Whitestone, Belfast

6-05: Creating artificially training data for AI detection of retinal microaneurysms (abstract 81)
Mr Simon Lyck Bjært Sørensen, Odense

6-06: Performance evaluation of software-assisted diabetic retinopathy screening (abstract 105)
Mr Tobias Nissen, Aalborg


7 - Medical and surgical treatment of diabetic retinopathy
Moderator: Professor Simon Harding, Liverpool


7-01: Pretraining on abstract modules on a virtual reality vitreoretinal simulator is a waste of time (abstract 56)
Ms Sarah Bjørn Petersen, Odense

Free-registration award-winning abstract for young scientist
7-02: Vitrectomy for sight-threatening diabetic retinopathy in Denmark 1999-2019: a national, registry-based study (abstract 31)
Dr Thomas Torp, Odense

7-03: Treating diabetic macular oedema: 12-weeks intervals in the first year (abstract 104)
Professor Tunde Peto, Belfast

7-05: Functional and structural efficacy of a novel combinational therapy of aflibercept and timely focal/grid photocoagulation in diabetic macular edema: do clinical study results compare favorably with a standard-of-care treated real-life population? (abstract 32)
Mr Mathias Jørgensen, Odense

7-08: Assessment of complications during the late postoperative period for patients with diabetes mellitus after drainage surgery of secondary neovascular glaucoma (abstract 49)
Ms Valeriya Biletskaya, Moscow

15:00 Keynote lecture: Translating epidemiological studies into clinical care in diabetes
  Professor Ryo Kawasaki, Osaka
15:30 Session 4: Clinical studies and novel treatments of diabetic retinopathy
  Chairs: Dr Stela Vujosevic, Milan, and Professor Tom Gardner, Ann Arbor
15:31 The levels of placental growth factor and other proteins in the vitreous of patients undergoing diabetic vitrectomy and the effect of bevacizumab as compared to aflibercept pre-treatment (abstract 93)
  Dr Ingeborg Klaassen, Amsterdam
15:42 The risk for developing vision threatening retinopathy after cataract surgery in diabetic patients depends on the post-operative follow-up time (abstract 98)
  Professor Toke Bek, Aarhus
15:53 Are there still indications for macular laser in diabetic macular oedema? (abstract 48)
  Ms Angela Dale, Gloucestershire 
16:04 Effect of calcium dobesilate in patients with subclinical diabetic macular edema: the CADODIAME study (abstract 23)
  Dr Olga Simó-Servat, Barcelona
16:15 Factors associated with the response to fluocinolone acetonide 0.19 mg in diabetic macular edema evaluated as the area-under-the-curve (abstract 15)
  Dr Maria Vittoria Cicinelli, Milan
16.26 Free-registration award-winning abstract for young scientist
  Macular function and structure in early diabetic retinopathy (abstract 87)
  Dr Jae Yee Ku, Liverpool 
16:37 Session conclusions by the moderators
16:40 Break
16:55 Key note lecture: Diabetic eye screening: one size does not fit all
  Professor Einar Stefánsson, Reykjavik
17:25 Annual General Meeting
  EASDec Board
18:00 End of the day
19:00 Conference dinner
  Restaurant Nordatlanten (North Atlantic Restaurant)
  Nordatlantisk promenade 1 (1.8 kilometer walk from conference venue)
  Dress code: Smart casual
  Social event registration needed for participation
  19:00 We meet at the conference venue and walk through the city to the restaurant
19:30 Arrival and welcome drink
20:00 Conference dinner
22:00 Coffee
22:30 Live band: Lasse Skov & Clazified
01:15 Late night snack
02:00 End of night



08:15 Registration
08:45 Session 5: Providing ocular and systemic prevention and care in diabetes
Chairs: Professor Rafael Simó, Barcelona, and Professor Kurt Højlund, Odense
08:46 Free-registration award-winning abstract for young scientist
  Early worsening of retinopathy in people with diabetes after rapid improvement in glycaemic control: a systematic review (abstract 46)
  Dr Handan Akil, Liverpool
08:57 MFAP4 immunotherapy-mediated inhibition of retinal neovascularization and vascular leakage (abstract 17)
  Dr Anders Schlosser, Odense
09:08 Diabetic retinopathy and skin tissue advanced glycation end products are biomarkers of vascular events in type 2 diabetic patients: results of the “PRECISED” study (abstract 22)
  Ms Alejandra Planas, Barcelona
  Free-registration award-winning abstract for young scientist
09:19 Long-term visual outcomes and morphologic biomarkers of vision loss in eyes with diabetic macular edema treated with anti-VEGF therapy (abstract 106)
  Dr Enrico Borrelli, Milan
09:30 Session conclusions by the moderators
09:33 Mini Symposium: Diabetic retinopathy in relation to ocular and systemic disease: pearls and pitfalls from a Danish national registry-linkage study
  Chair: Professor Jakob Grauslund, Odense
  Expert panel: Professor Kurt Højlund (the diabetologist), Professor Tunde Peto (the ophthalmologist)
09:34 The Ocular And Systemic complications In diabetic retinopathy Study (OASIS): study design and methodology
  Professor Jakob Grauslund, Odense
09:42 Rapid fire presentation 1: DR as a marker of neurodegenerative disease
  Dr Frederik Nørregaard Pedersen, Odense
09:48 Rapid fire presentation 2: DR as a marker of cardiovascular disease
  Ms Lonny Stokholm, Odense
09:54 Rapid fire presentation 3: DR as a marker of ocular disease
  Dr Sebastian Dinesen, Odense
10:00 Panel discussion: what can be learned from big data, register-linking studies?
10:10 Keynote Lecture: A journey through multi-omics analyses of diabetic retinopathy
  Associate Professor Patrice Fort, Ann Arbor
10:55 Coffee Break
11:15 Session 6: Novel methods in retinal imaging
Chairs: Professor Tunde Peto, Belfast, and Professor Jakob Grauslund, Odense
11:16 OCTA metrics monitor severity progression of diabetic retinopathy (abstract 29)
  Professor José Cunha-Vaz, Coimbra
11:27 Ganglion cell-inner plexiform layer alteration in the initial stages of diabetic retinopathy in type 2 diabetic patients: a 5-year longitudinal study (abstract 42)
Dr Inês Marques, Coimbra
11:38 Microaneurysm Turnover in eyes with mild nonproliferative diabetic retinopathy is associated with progression and development of sight-threatening complications: a 5-year longitudinal study (abstract 100)
  Dr Ana Rita Santos, Coimbra
11:49 Three-year OCT-angiography evaluation in patients with diabetes mellitus type 1 and 2 without clinical signs of diabetic retinopathy and with good glycemic control (abstract 62)
  Dr Stela Vujosevic, Milan
12:00 Session conclusions by the moderators
12:03 Session 7: Entering the era of artificial intelligence in diabetic eye screening
Chairs: Professor Frank Verbraak, Amsterdam, and Professor Rajeeth Savarimuthu, Odense
12:04 Development of an artificial intelligence-based diabetic retinopathy screening tool for OPTOS ultra-widefield imaging (abstract 107)
  Professor Tunde Peto, Belfast
12:15 Trustworthy AI: closing the gap between development and integration of AI in Ophthalmology (abstract 66)
  Ms Cristina González-Gonzalo, Amsterdam
12:26 Accuracy of a diabetic retinopathy grading algorithm used with a hand-held fundus camera in Southern Malawi (abstract 99)
  Dr Joe Aslan, Zomba
12:37 Testing of thirteen artificial intelligence algorithms for diabetic retinopathy using fundus images from Finland (abstract 69)
  Dr Petri Huhtinen, Oulo
12:48 Session conclusions by the moderators
12:51 Best poster prize ceremony and closing remarks
President of EASDec, Professor Rafael Simó, Barcelona
13:00 Conference close and lunch to go